Integra® Dermal Regeneration Template, available in Meshed and Non-Meshed configurations (Integra® Template) is a bilayer membrane system for skin replacement. The dermal replacement layer is made of a porous matrix of fibers of cross-linked bovine tendon collagen and glycosaminoglycan (chondroitin-6-sulfate) that is manufactured with a controlled porosity and defined degradation rate. The epidermal substitute layer is made of thin polysiloxane (silicone) layer to control moisture loss from the wound.

This video illustrates the process of dermal regeneration from a full-thickness burn injury.

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Benefits of INTEGRA^® Template include:

• The permanent regeneration of dermal skin
  
• Thinner skin grafts resulting in less scarring at the donor site
  
• Faster healing donor sites
  
• Immediate physiological wound closure without risking the loss of donor material
  
• Patients can begin rehabilitation with INTEGRA^® Template in place
  
• No reports of rejection
  
• No immediate need to create donor site wounds
  
• Donor sites heal faster and can be harvested more frequently
  
• Post excisional use of INTEGRA^® Template does not require the use of temporary
  coverings such as allograft, xenograft or synthetic dressings

These results have been confirmed by frequent patient follow-ups over a 10-year period.

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