Product Description and Benefits
  Indications for Use
  Product Makeup/Histology
  Clinical Sequence
    Venous Stasis Ulceration
    Trans-metatarsal amputation
    Traumatic degloving calcaneal fracture
    Stump Salvage
    Achilles Ulcer
    Exposed Bone
    Chronic Venous Ulceration
    Immunopathic Wound
    Exposed Joint
    Limb Salvage
    Leg Ulceration
    Arterial Disease
    Hypercoagulable Disorder
    Ankle Ulcer
    Ischemic Ulceration
    Forefoot Ulceration
    Heel Ulcer

Ulceration to both feet and anterior ankles
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A 62-year-old African American female was referred to the wound care center with ulceration to both of her feet and anterior ankles

Electrical/flame burn to neck

The wounds were previously treated with operative debridements, followed by wound VAC application. Initial treatment at our center
included debridement of the wounds with incisional skin biopsy,
followed by application of a split thickness skin graft. The right foot
healed uneventfully, while the left skin graft did not take

Fascial excision of chest

The pathology report suggested the etiology to be vasculitis (unidentified type). At this point, tendons were exposed in
the wound, and the decision was made for further debridement with excision of the tendons

INTEGRA® Dermal Regeneration Template

Application of INTEGRA™ Bilayer Matrix Wound Dressing. Three weeks later, the dressing had taken and was flush with the skin

Elastic net dressing

A split thickness skin graft was again attempted

2 years post trauma

On second attempt, the skin graft had taken, and healed uneventfully

Results of epidermal graft
Cases Courtesy of:
Dave Granger D.P.M., Kevin Roberts D.P.M., Richard Jay D.P.M., Mark Mantell M.D., Paul Glat, M.D.
The Graduate Hospital Wound Care Center, Philadelphia, PA 19146

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