A prepared wound bed must be free
from contamination and infection. All necrotic and devitalized
tissue must be removed. Pre-Operative routines should
follow normal surgical center protocols. This may include
the use of systematic broad spectrum antibiotics. If
wound infection is detected, treat topically and/or
systemically according to unit protocols.
Achieve an adequate vascular supply
prior to the application of INTEGRA
Bilayer Matrix Wound Dressing. Punctate,
uniform capillary bleeding indicates adequate removal
of the affected tissue. Signs of a viable wound bed
include: white dermis, pure yellow fat and glistening
The wound bed must be dry with no
signs of bleeding. Meticulous hemostasis needs to be
achieved to prevent hematomas or excessive fluid accumulation.
Epinephrine, pinpoint electrocaudary, thrombin spray,
thrombin-soaked gauze or other topical hemostats should
be used. Avoid broad area cauterization which can lead
to devitalized tissue.
To ensure intimate contact with INTEGRA
Bilayer Matrix Wound Dressing the wound
bed must be uniform and flat. Achieve level tissue planes
and when necessary, marsupializing edges to avoid large
step-offs between the wound bed and normal skin.
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